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Cancers arising from uterine fibroids are called leiomyosarcomas. The overall risk of fibroids being cancerous (malignant) is approximately one in 1,000 (of removed fibroids) in the reproductive years and is more common in postmenopausal women. A fibroid that grows after menopause may be a leiomyosarcoma, in which case removal of the uterus (hysterectomy) is required.

You can find more information from the American Society for Reproductive Medicine on this topic here:

http://www.reproductivefacts.org/uploadedFiles/ASRM_Content/Resources/Patient_Resources/Fact_Sheets_and_Info_Booklets/what%20are%20fibroids%20FINAL%204-23-12.pdf

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